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Topamax has long been indicated to treat seizures in epileptic patients. Only recently, it has been used as an alcohol treatment in patients experiencing with cravings and addiction. Topamax works by blocking the dopamine receptors used by alcohol and by blocking these receptors, Topamax is used as an alcohol treatment to minimize the relapse chances in patients. Since dopamine receptors are blocked, the alcoholic receives no pleasure or the high that is accomplished when drinking even the few amount of alcohol. Some patients appreciate that the alcohol treatment is in pill form, making it easy for addicts to use the drug.

Topamax is the brand name for the drug topiramate and this drug was first developed in 1979 to cure seizures. It’s also indicated to treat severe migraines. For alcohol treatment, Topamax works in two forms. The medication is an antagonist for dopamine receptors. An antagonists attaches to receptors in the brain and block its activity and when activity is block, it limits the dopamine production and activity, which limits the pleasurable effects of alcohol when consumed.

The second effect Topamax has in the brain is its block in dopamine production by limiting the amino acid glutamate. Glutamate is a precursor to dopamine, so its inhibition minimizes the amount of dopamine in the brain. The lower levels of dopamine after drinking lessen the high which is an effective alcohol treatment. Without the high, patients no longer crave the medication.

Topamax has shown to level blood pressure in alcoholics. One of the main adverse effects of alcoholism in the liver toxicity and high blood pressure shown in patients who binge drink or have habitual long-term heavy drinking. High blood pressure is the cause of heart disease and damages kidneys. These adverse effects are the main cause for the high morbidity rates in alcoholics. An effective alcohol treatment reverses these effects, allowing the patient a better quality of life and better chances for survival from long-term alcohol consumption.